Preheat oven to 350 degrees F.
Make the pretzel crust. In a food processor, process about 1 ½ cups of pretzels until they become fine crumbs, Measure ¾ cup crumbs and combine with whole wheat flour and butter. Pulse in a food processor until the mixture resembles coarse sand. Add 4 tablespoons of water, pulsing the mixture just until combined. If the mixture is too dry, add an additional tablespoon of water. Gently knead the dough into a disc and wrap it with plastic wrap. Chill in the fridge for 30 minutes or up to overnight.
Meanwhile, make the cream cheese filling. Beat together the softened cream cheese with egg yolk, sugar, and vanilla until smooth. Set aside.
Gently toss the strawberries with honey, cornstarch, and orange zest. Set aside.
Lightly dust a clean work counter with flour. Remove the pretzel dough from the fridge and roll it until it's about ⅛ inch thick. Spread the cream cheese filling over the dough in an even layer, leaving a 1-inch border. Top the cream cheese with the strawberries and fold the edges of the dough over the filling. Brush the crust with the egg wash and sprinkle coarse sugar over the dough.
Bake the galette in the oven for 45 minutes - 1 hour or until the crust is golden and the fruit is caramelized. Let cool slightly and serve warm or at room temperature.