Preheat oven to 350 degrees F. Line a baking sheet with parchment paper.
Combine strawberries with honey in a medium saucepot. Bring to a simmer over medium heat. Reduce heat to low and continue to cook until strawberries are softened and liquid has reduced by half, about 15 minutes. Stir occasionally to prevent the bottom of the pot from burning. Remove from heat and stir in vanilla extract. Let cool completely.
Puree strawberries until smooth. Measure 6 tablespoons (80 grams) of the puree and set aside the remaining.
Combine 6 tablespoons (80 grams) strawberry sauce with softened butter and brown sugar in a food processor. Pulse together until mixture is smooth.
Cut and remove the crusts from the bread. Spread strawberry honey butter in an even layer on all sides of the bread, including the edges. Arrange toast on prepared baking sheet in an even layer.
Bake toast for 18-20 minutes, carefully flipping over toast halfway through. Remove from oven and let cool for 10 minutes.
Serve strawberry honey butter toast with vanilla cream and top with fresh berries. Drizzle reserved strawberry sauce and serve immediately.